H-2-LINKED IMMUNE RESPONSE (Ir) GENES
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چکیده
منابع مشابه
H-2-LINKED IMMUNE RESPONSE (Ir) GENES
Two H-2-linked autosomal dominant immune response (Ir) genes Ir-IgG and Ir-IgA were demonstrated to be at separate loci. Ir-IgG controls the immune response to IgG (gamma2a) myeloma proteins and Ir-IgA the immune response to IgA meyloma proteins. Both genes are associated with the H-2K region specificities of the H-2 chromosome, specifically Ir-IgG with H-2(b) and Ir-IgA with H-2(a). Different ...
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متن کاملPhosphoproteins recognized by an H-2-linked immune response gene and their association with cell proliferation.
An H-2-associated immune response gene which maps to the I-A subregion of the H-2 complex governs the ability of H-2 congenic mice to mount an antibody response to five phosphoproteins with molecular weights of 33,000, 29,000, 23,000, 17,000, and 16,000 when inoculated with BW5147, a spontaneous AKR T-cell leukemic cell line. The phosphoproteins are present in all tumor cell lines tested, inclu...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1972
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.136.5.1231